Febee Louka

Febee Louka
  • Faculty
  • Professor

Education

Ph.D. in Analytical (electrochemistry/Medicinal Chemistry], 2004
Ohio University, Athens, OH 45701
Thesis title: “Interdependence of Endothelium Dysfunction and the Lifespan of the Cardiovascular System” supervised by Prof. Tadeusz Malinski

M.Sc. (Physical Organic Chemistry), 1996
Alexandria University, Alexandria, Egypt

B.Sc. (Chemistry), 1985
Alexandria University, Alexandria, Egypt

Student Research/Collaboration

  • Synthesis of polynuclear Cu(II), Co(II), Mn(II), and Ni(II) complexes used in the DNA cleavage and anticancer.
  • Monitoring the environmental pollution caused by chlorinated hydrocarbons and petroleum hydrocarbons in biota and sediment samples using gas chromatography technique. [Certified Trainee by Marine Environment Laboratories (Monaco) International Atomic Energy Agency] 1992-1998.
  • Extraction and removal of pollutants from environmental samples and removal of oil spills from environmental systems.
  • Fabrication of microsensors for direct electrochemical measurements of nitric oxide, superoxide and peroxynitrite in biological samples from rats, mice and rabbits.
  • Synthesis of surfactants that can be used for preventing pesticides and polycyclic aromatic hydrocarbons from penetrating the soil layer and reach the plants roots.
  • Synthesis of porphyrin analogs and metal complexes that can be used as coatings for microsensors.
  • Dye removal using ecofriendly adsorbents.
  • Extraction and purification of β-carotene and ascorbic acid from different types of algae. Characterization of these antioxidants using high performance liquid chromatography and spectrophotometric techniques.
  • Hands on GC, GC-MS, Atomic absorption, ICP, and UV-vis instruments.

Publications

  • Wiemer, G.; Dobrucki, L. W.; Louka, F. R.; Malinski, T.  Heitsch, H., AVE 0991, a Nonpeptide Mimic of the Effects of Angiotensin-(1-7) on the Endothelium. Hypertension 2002, 40, 847-52. 
  • Balbatun, A.; Louka, F. R.; Malinski, T.  Dynamics of Nitric Oxide Release in the Cardiovascular System. Acta Biochimica 2003, 50(1), 61-67.
  • Massoud, S. S.; Jeanbatiste, R. R.; Nguyen, T. M.; Louka, F. R.; Gallo, A. A., “Cobalt(III) Complexes of Tripod Amines. Kinetics of Aquation of Dichloro[N-(2aminoethyl)-N,N-bis(3 aminopropyl)amine]cobalt(III) Ion”. J. Coord. Chem. 2007, 60, 2409-2419.
  • Mautner, F. A.; Vicente R.; Louka, F. R.; Massoud, S. S. “Dinuclear Fumarato- and Terephthalato-bridged Copper(II) Complexes. Structural Characterization and Magnetic Properties”. Inorg. Chim. Acta, 2008, 361(5), 1339-1348. 
  • Massoud, S. S.; Mautner, F.A.; Vicente, R.; Louka, F. R. “Squarato-metal(II) Complexes. Part 3: ÎĽ1,3- (trans) vs. ÎĽ1,2- (cis) bonding in Squarato-bridged Dinuclear Copper(II) and Nickel(II) Complexes dreived from Polypyridyl Amines”. Eur. J. Inorg. Chem. 2008, 23, 3709 – 3717. 
  • Louka, F. R.; Mautner, F. A.; Vicente, R.; Massoud, S. S. “μ2-Oxalato-bridged Tricopper(II) Complex Derived from 1,4,8,12-Tetraazacyclopentadecane.Synthesis, Structure and Magnetic Characterization”. Inorg. Chem. Commun.  2008, 11(4), 438 441. 
  • Mautner. F. A.; Louka, F. R.; LeGuet, T.; Massoud, S. S. “Pseudohalide Copper(II)Complexes Derived from Polypyridyl Ligands. Synthesis and Characterization”.  J. Molecular Struct. 2009, 919, 196–203. 
  • Xu, W.; Louka , F. R.; Doulain, P. E.; Landry, C. A.; Mautner, F. A.; Massoud, S. S. and “Hydrolytic Cleavage of DNA Promoted by Cobalt(III)-Tetraamine Complexes. Synthesis Characterization of Carbonatobis[2-(2-pyridylethyl)]-(2
    pyridylmethyl)aminecobalt(III) Perchlorate”.  Polyhedron 2009, 28, 1221–1228.  
  • Massoud, S. S.; Louka, F. R.; Mikuriyab, M.; Ishidab, H.; Mautner. F. A. "Dicyanamido– metal(II) complexes. Part 3: Hydrolysis of the dicyanamide into amidocyanamide". Inorg. Chem. Commun.  2009, 12(5), 420-425. 
  • Mautner. F. A.; Louka, F. R.; Massoud, S. S. “Structural characterization of some oxalato-bridged copper(II) and nickel(II) complexes". J. Molecular Struct. 2009, 921(1-3), 333-340. 
  • Mautner, F. A.; Masahiro Mikuriya, M., Ishida, H.; Louka, F. R.; Humphrey, J. W.; 
  • Massoud, S. S., “Dicyanamido-Metal(II) Complexes. Part 4. Synthesis, Structure and Magnetic Characterization of Polynuclear” Inorg. Chim. Acta 2009, 362(11), 40734080.  
  • Mason R. P.; Kubant, R.; Jacob, R. F.; Malinski, P., Huang, X.; Louka, F. R.; Borowiec, J.; Mizuno, Y.; Malinski, T.  â€śLoss of Arterial and Renal Nitric Oxide Bioavailability in Hypertensive Rats with Diabetes: Effect of β-Blockers” American Journal 
    Hypertension 2009, November 22(11), 1160-1166. 
  • Mautner, F. A.; Louka, F. R.; Gallo, A. A., Saber, M. R., Burham, N. B., Albering, J. H.; Massoud, S. S. “Thiocyanato-Cu(II) Complexes Derived from Tridentate Amine Ligands and from Alanine” Transition Met. Chem. 2010, 35(5), 613- 620. 
  • Mautner, F. A.; Albering, J. H.; Vicente, R.; Louka, F. R.; Gallo, A. A.; Massoud, S. S. “Copper(II) Complexes Derived from Tripodal Tris[(2-ethyl-(1-pyrazolyl)]amine”. Inorg. Chim. Acta 2011, 365(1), 290-296. http://dx.doi.10.1016/j.ica.2010.09.030
  • Massoud, S. S.; Louka, F. R.; Nguyen, T.L.; Mikuriya, M.; Albering, J. H.; Mautner, F. A. “Structural and Magnetic Characterization of 1-D Copper Complexes Constructed from Pyrazole-3,5- dicarboxylate Bridging Multi Cu(II) Centers”  Inorg. Chim. Acta 2011, 366(1), 394-398. http://dx.doi.10.1016/j.inoche.2011.02.011 
  • Massoud, S. S.; Mautner, F. A.; Louka, F. R.; Demeshko, S.; Dechert, S.; Meyer, F., “Diverse Coordination of Polynuclear Copper(II) Complexes Constructed from Benzene Tetracarboxylate” Inorg. Chim. Acta, 2011, 370, 435-443. http://dx.doi.10.1016/j.ica.2011.02.019  
  • Mautner, F. A.; Albering, J. H.; Corbella, M.; Louka, F.R.; Massoud, S. S. “A Unique Unit Cell Containing Simultaneous Doubly and Triply Copper(II) Complexes Bridging by 2,4-Pyridine Dicarboxylate.  Synthesis, Structural Characterization and Magnetic Properties” Inorg. Chem. Commun., 2011, 14, 702-705.  http://dx.doi.10.1016/j.inoche.2011.02.011 
  • Louka, F. R.; Spell, M. L.; Grebowicz, J.; Albering, J. H.; Mautner, F. A.; Massoud, S.S. “Coordination Chemistry of 1,4-Bis[bis(2-pyridylmethyl)aminomethyl]benzene with Copper(II)” J. Mol. Struct., 2011, 995, 103-108. http://dx.doi.10.1016/j.molstruc.2011.03.066 
  • Massoud, S. S.; Louka, F. R.; Xu, W.; Perkins, R.; Vicente, R.; Albering, J. H.; Mautner, F. A., “DNA Cleavage by Structurally Characterized Dinuclear Copper(II) Complexes Based on Triazine” Eur. J. Inorg. Chem., 2011, 3469-3479. http://dx.doi.10.1002/ejic.201100157  
  • Mason, R. P.; Jacob, R. F.; Kubant, R.; Jacoby, R.; Louka, F. R.; J. Corbalan, J.; Malinski, T. “Effects of Angiotensin Receptor Blockers on Endothelial Nitric Oxide Release — The Role of eNOS Variants” Br. J. Clin. Pharmacol. 2012, 74(1), 141-6. doi: 10.1111/j.1365-2125.2012.04189. x. 21. Louka, F. R.; Nguyen, T. L.; Albering, J. H.; Mautner, F. A.; Massoud, S. S. “Unprecedented formation of a doubly bridged ÎĽ-peroxo-ÎĽ-  pyrazolyldicarboxylatodicobalt(III) complex”. Inorg. Chem.Commun. 2012, 15, 269271. 
  • Louka, F. R.; Stewart, A. D.; Regel, E.; Mautner, F. A.; Demeshko, S.; Meyer, F.; Massoud, S.S., “Squarato-Metal(II) Complexes: Part 5. Polynuclear Copper(II) Complexes Bridged by Squarate and Croconate Dianions”. Inorg. Chem. Commun. 2012, 22, 60–64. 
  • Massoud, S. S.; Louka, F. R.; Obaid,  Y. K Vicente, R.; Ribas, J; Fischer, R. C.; Mautner, F. A. “Metal ions directing the geometry and nuclearity of azido-metal(II) complexes derived from bis(2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl)amine” Dalton Transactions 2013, 42, 3968-3978. http://dx.doi:10.1039/C2DT32540C. 
  • Mautner, F. A.; Louka, F. R.; Hofer, J.; Spell, M.; Lefèvre, A.; Guilbeau, A. E.; Massoud, S. S. “One-Dimensional Cadmium Polymers with Alternative di(EO/EE) and di(EO/EO/EO/EE) Bridged Azide Bonding Modes”. Crystal Growth & Design, 2013, 13 (10), 4518–4525.http://dx.doi.org/10.1021/cg400998r 
  • Massoud, S. S.; Perkins, R.; Louka, F. R.; Xu, W.; Roux, A, L; Dutercq, Q; Fischer, R. C.; Mautner, F. A.; Handa, H.; Hiraoka, Y.; Kreft, G. L.; Bortolottoe, T.; Terenzi, H. “Efficient hydrolytic cleavage of plasmid DNA by chloro-cobalt(II) complexes based 
    on sterically hindered pyridyl tripod tetraamine ligands: synthesis, crystal structure and DNA cleavage” Dalton Transactions, 2014, 43, 10086–10103. 
  • Mautner, F. A.; Mikuriya, M.; Naka, N.; Louka, F. R.; Massoud, S. S. “Bonding ÎĽ1,3- (trans) vs ÎĽ1,2- (cis) in squarato-bridging dinuclear copper(II) complexes derived from pyridyl amine ligands”. Polyhedron, 2015, 85, 110–116. http://dx.doi:10.1016/j.poly.2014.08.040 
  • Massoud, S. S.; Louka, F. R.; David, R. N.; Dartez, M. J.; Nguyn, Q. L.; Labry, N. J. Fischer, R. C.; Mautner, F. A.; “Five-coordinate metal(II) complexes based pyrazolyl ligands” Polyhedron, 2015, 90, 258–265. 
  • Massoud, S. S.; Louka, F. R.; Abu-Elhassan, M. A.; Vicente, R.; Mautner, F. A. “Magneto-structural properties of carbonato-bridged copper(II) complexes. Fixation of atmospheric CO2” New J. Chem. 2015, 39, 5944-5952. 
  • Massoud, S. S.; Louka, F. R.; Mautner, F. A. “Polynuclear and Polymeric SquaratoBridged Coordination Compounds” Cryst. Eng. Comm. 2015, 17, 7604-7617. 
  • Massoud, S. S.; Junk, T.; Louka, F. R.; Herchel, R.; Travnicek, Z.; Fischer, R.; Mautner, F. A. “Synthesis, structure and magnetic characterization of dinuclear copper(II) complexes bridged by bicompartmental phenolate” RSC Adv. 2015, 5, 
    87139-87150. 
  • Massoud, S. S.; Louka, F. R.; Gazzaz, M. A.; Henary, M. M.; Fischer R. C.; Mautner, F. A. “Polynuclear copper(II) complexes bridged by polycarboxylates of aromatic and N-heterocyclic compounds” Polyhedron 2016, 111, 45-52. Herchel, R.; Dvořák, Z.; TrávnĂ­ÄŤek, Z.; Mikuriyab, M.; Louka, F. R.; Mautner, F. A.; Massoud, S. S. “Massoud “Cobalt(II) and copper(II) covalently and non-covalently dichlorido-bridged complexes of an unsymmetrical tripodal pyrazolylpyridyl amine ligand: structures, magnetism and cytotoxicity” Inorg. Chim. Acta 2016, 451, 102110. 
  • Satbhai, K. M.; Louka, F. R.; Klerks, P. L. “Individual and combined effects of petroleum hydrocarbons phenanthrene and dibenzothiophene on reproductive behavior in the amphipod Hyalella azteca” Journal Water, Air & Soil Pollution 2017, 228: 91. DOI 10.1007/s11270-017-3276-x 
  • Massoud, S. S.; Louka, F. R.; Mautner, F. A. “Structural characterization of metal(II) thiocyanato complexes derived from bis(2-(H-pyrazol-1-yl)ethyl)amine” Polyhedron 2017, 124, 237-242. 
  • Massoud, S. S.; Williams, G. F.; Louka, F. R.; Henary, M. M.; Herchel, R.; TrávnĂ­ÄŤek, K.; Fischer, R. C. Mautner, F. A. “Croconato-bridged copper(II) complexes. Synthesis, structure and magnetic characterization” New J. Chem., 2017, 41, 3846
    3856. http://dx.doi:10.1039/C6NJ03943J 
  • Louka, F. R.; Osman, S. Y.; Terracina, T.; Khamidullina, N. “Assessing Ecofriendly Wastes in Removal of Pyrene as a Model of Oil Spills” International Journal of chromatography and separation techniques 2017, 1, J102-106. 
  • Louka, F. R.; Massoud, S. S.; Haq, T. K.; Henary, M. M.; Vicente, R.; Fischer, R. C.; Mautner, F. A. “Synthesis, structural characterization and magnetic properties of onedimensional Cu(II)-azido coordination polymers” Polyhedron. 2017, 138, 177-184. 
     
  • Louka, F. R.; Junk, T.; Massoud, S. S., “DNA Cleavage by Bicompartmental Dinuclear Metal(II) Complexes”. J. Biolog. Inorg. Chem. 2017, 22, S137-S137. 
  • Massoud, S. S.; Louka, F. R.; Ducharme, G.; Fischer, R.; Mautner, F. A.; Vanco,J.; Herchel, R.; TrávnĂ­ÄŤek, K.;  â€śCopper(II) complexes based on tripodal pyrazolyl amines: Synthesis, structure magnetic properties and anticancer activity” Journal of Inorganic Biochemistry.  2018, 108, 36-46. 
  • Klerks, P. L.; Kascak, A.; Cazan A. M.; Deb Adhikary, N.; Chistoserdov, A.; Shaik,A.; Osman, S. Y.; Louka, F. R. “Effects of the razor clam Tagelus plebeius on the fate of petroleum hydrocarbons; a mesocosm experiment” Archives of Environmental Contamination and Toxicology in press 2018.

Awards & Recognition

  • April 2018: Eminent Award, Dr. Ray P. Authement Excellence in Teaching, Â鶹ҹĘĐ, LA
  • February 2018: Outstanding Faculty of Universities of Louisiana System 2018.
  • Fall 2017 - present: Member in University Senate
  • 2017: Awardee of Awardee of Royal Society of Chemistry Books for contents. organization and presentation in ICBIC 18th, FlorianĂłpolis, Brazil.